Intraepithelial carcinoma (Bowen disease) - I-Intraepithelial Carcinoma (Isifo Se-Bowen)
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Kwiziphumo zika-2022 ze-Stiftung Warentest ezivela eJamani, ukwaneliseka kwabathengi ngeModelDerm bekungaphantsi kancinci kunokubonisana nge-telemedicine ehlawulweyo.
Imeko eqhelekileyo ― I-Intraepithelial Carcinoma (Isifo Se-Bowen) (Intraepithelial carcinoma (Bowen disease)) ingaqwalaselwa njenge-eczema ehlala ixesha elide, engarhawuzeli.
relevance score : -100.0%
ReferencesBowen's disease (BD) luhlobo lomhlaza wolusu oluqala kumphandle wolusu (epidermis). Ixhaphake kakhulu kubantu baseCaucasian kwaye ihlala isenzeka kwiindawo ezichache elangeni, kodwa inokuvela nakwezinye iindawo. I‑BD ibonakala njengesilonda esinye. I‑BD isoloko ibonwa njengophawu lwesilumkiso phambi kokuba kuvele uhlobo olubi kakhulu lomhlaza wolusu. Ukuxilonga i‑BD, oogqirha bahlala bexhomekeke ekuhloleni iisampulu zezicubu phantsi kwe‑microscope (biopsy).
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease ikakhulu ichaphazela abantu abamhlophe abaneminyaka engaphezu kwama-60. Imiba ephambili yomngcipheko ibandakanya ukuchengela kwelanga ixesha elide, ukuncipha kokhuseleko lomzimba, ukuvezwa kwe-arsenic, kunye nosulelo lwe-HPV yesikhumba. Iintlobo ze-HPV 16, 18, 34, kunye ne-48 zinxulunyaniswa nesifo sika-Bowen kwiindawo zangasese. Ukubandakanyeka kwe-HPV kwiimeko ezingezizo ezesini akucacanga kangako.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Ngokuqhelekileyo ibonakala njengendawo ebomvu, ene-scaly okanye e-crusty naphi na emzimbeni. Indawo eqhelekileyo yimilenze ephantsi.
Iyanyangeka ngeendlela ezahlukeneyo zonyango ezifana ne-cryotherapy, curettage (curettage), i-cautery, unyango lwe-photodynamic, okanye ukukhutshwa kwesilonda.
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#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy